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1,1'-Carbonyldiimidazole

CAS No.
530-62-1
Chemical Name:
1,1'-Carbonyldiimidazole
Synonyms
CDI;CARBONYLDIIMIDAZOLE;1,1'-CARBONYLDIIMIDAZOLE (CDI);DI(1H-IMIDAZOL-1-YL)METHANONE;N,N-CARBONYLDIIMIDAZOLE;Diimidazolyl ketone;1,1-CARBONYL DIIMIDAZOLE;5% Pd-BaSO4;CARBODIIMIDAZOLE;Di-imidazol-1-yl-methanone
CBNumber:
CB0215374
Molecular Formula:
C7H6N4O
Molecular Weight:
162.15
MDL Number:
MFCD00005286
MOL File:
530-62-1.mol
MSDS File:
SDS
Modify Date:2023-03-29 09:07:45

1,1'-Carbonyldiimidazole Properties

Melting point 117-122 °C(lit.)
Boiling point 288.83°C (rough estimate)
Density 1.303 g/mL at 25 °C
vapor pressure 0.006-0.012Pa at 20-25℃
refractive index n20/D1.434
storage temp. 2-8°C
solubility Soluble in dimethylformamide.
form Crystalline Powder
pka 2.90±0.10(Predicted)
color White to light cream
PH Range 7.7 at 50 g/l
PH 7.7 (50g/l, H2O, 20℃)
Water Solubility Insoluble in water
Sensitive Moisture Sensitive
Merck 14,1819
BRN 6826
Stability Stable, but moisture-sensitive. Incompatible with acids, strong oxidizing agents, water.
InChIKey PFKFTWBEEFSNDU-UHFFFAOYSA-N
CAS DataBase Reference 530-62-1(CAS DataBase Reference)
FDA UNII 63A10X1FSP
EPA Substance Registry System 1H-Imidazole, 1,1'-carbonylbis- (530-62-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07,GHS08
Signal word  Danger
Hazard statements  H302-H314-H360D
Precautionary statements  P260-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  C,Xi,Xn
Risk Statements  22-34-36/37/38-40-36/38
Safety Statements  26-36/37/39-45-37/39-27-36/37
RIDADR  UN 3263 8/PG 2
WGK Germany  2
10-21
Hazard Note  Harmful/Corrosive/Moisture Sensitive
TSCA  T
HazardClass  8
PackingGroup  III
HS Code  29332990
Toxicity LD50 orally in Rabbit: 1071 mg/kg
NFPA 704
1
3 1

1,1'-Carbonyldiimidazole price More Price(68)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.02301 1,1′-Carbonyldiimidazole for synthesis 530-62-1 2G $31.1 2023-01-07 Buy
Sigma-Aldrich 8.51054 CDI 1,1′-Carbonyldiimidazole Novabiochem? 530-62-1 25g $163 2023-01-07 Buy
Sigma-Aldrich 8.51054 CDI 1,1′-Carbonyldiimidazole Novabiochem? 530-62-1 100g $486 2023-01-07 Buy
Sigma-Aldrich 8.02301 1,1′-Carbonyldiimidazole for synthesis 530-62-1 5G $32.2 2023-01-07 Buy
Sigma-Aldrich 8.02301 1,1′-Carbonyldiimidazole for synthesis 530-62-1 25G $117 2023-01-07 Buy
Product number Packaging Price Buy
8.02301 2G $31.1 Buy
8.51054 25g $163 Buy
8.51054 100g $486 Buy
8.02301 5G $32.2 Buy
8.02301 25G $117 Buy

1,1'-Carbonyldiimidazole Chemical Properties,Uses,Production

Chemical Properties

White crystalline powder

Uses

Used in the synthesis of peptides. Contains up to 10% imidazole.

Uses

peptide coupling reagent

Uses

CDI is mainly employed to convert alcohols and amines into carbamates, esters, and ureas. It is also used in the synthesis of peptides and nucleoside triphosphates.

Uses

1,1'-Carbonyldiimidazole is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.

Uses

Peptide coupling reagent1,1'-Carbonyldiimidazole acts as a coupling reagent and utilized for coupling of amino acids in order to prepare peptide in organic synthesis. It is also used in the preparation of beta-keto sulfones, sulfoxides and beta-enamino acid derivatives. It is used to convert alcohols and amines into carbamates, esters, and ureas. It is involved in the preparation of formylized imidazole by reaction with formic acid. Further, it is used in the synthesis of dipolar polyamides compounds. In addition to this, it is considered as an equivalent of phosgene and used to prepare asymmetric bis alkyl carbonate.

General Description

1,1′-Carbonyldiimidazole (N,N′-carbonyldiimidazole) is a versatile peptide-forming reagent.

Purification Methods

Crystallise it from *benzene or tetrahydrofuran in a dry-box and store it dry. [Hearn Methods Enzymol 135 102 1987, Beilstein 23/4 V 245.]

1,1'-Carbonyldiimidazole Suppliers

Global( 971)Suppliers
Supplier Tel Email Country ProdList Advantage
BTC Nantong Pharmaceuticals Technology Co.,Ltd
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LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24788 58
Coresyn Pharmatech Co., Ltd.
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View Lastest Price from 1,1'-Carbonyldiimidazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,1'-Carbonyldiimidazole pictures 2023-03-28 1,1'-Carbonyldiimidazole
530-62-1
US $42.00-38.00 / kilograms 10kilograms 99% 100tons Hebei Dangtong Import and export Co LTD
1,1'-Carbonyldiimidazole pictures 2023-03-28 1,1'-Carbonyldiimidazole
530-62-1
US $5.00 / kg 1kg 99% 200mt Jinan Finer Chemical Co., Ltd
N,N-Carbonyldiimidazole pictures 2023-03-24 N,N-Carbonyldiimidazole
530-62-1
US $90.00 / KG 1KG >99% 50000kg/Month Weijer International Trade (Hebei) Co., Ltd
CARBONYLDIIMIDAZOLE CARBODIIMIDAZOLE LABOTEST-BB LT00233203 IM2 C O DI(1H-IMIDAZOL-1-YL)METHANONE CDI (DIIMIDAZOL-1-YL)KETONE AKOS BBS-00004316 RARECHEM AK HZ 0060 1,1'-CARBONYLBIS-1H-IMIDAZOLE 1.1'-CARBONYL-BIS-IMIDAZOLE 1,1-CARBONYL DIIMIDAZOLE 1,1'-CARBONYLDIIMIDAZOLE 1H-IMIDAZOLE, 1,1'-CARBONYLBIS- N,N'-CARBONYLDIIMIDAZOLE N,N-CARBONYLDIIMIDAZOLE 1,1’-carbonylbis-1h-imidazol 1,1’-Carbonyldiimidazol 1,1'-Carbonylbis-1H-imidazole [Coupling Agent for Peptides Synthesis] 1,1'-Carbonyldiimidazole [Coupling Agent for Peptides Synthesis] 1,1'-Carbonyldi(1H-imidazole) Bis(1H-imidazol-1-yl) ketone Bis(1-imidazolyl) ketone carbonyl-1,1’-bis-1H-diimidazole 1,1'-Carbonyldiimidazole,97% 1’-Carbonyldiimidazole 1,1'-Carbonyldiimida Di-imidazol-1-yl-methanone 1,1'-CarbonyldiiMidazole, >90% N'-CarbonyldiiMidazole (CDI) Product 2: N,N'-CarbonyldiiMidazole N,Nzzhlxy-Carbonyldiimidazole (CDI) CDI (Carbonyl Diimidazole) N,N-Carbonyldiimidazole Manufacturer 5% Pd-BaSO4 1,1'-CARBONYLDIIMIDAZOLE (CDI) CARBONYLDIIMIDAZOLE N,N carbonylimidazole CDI (N,N'-Carbonyldiimidazole) 1,1-Carbonyldiimidazole99% N,N'-Carbonyldiimidazole, 98%+ N,N'-Carbonyl diimidazole (CDI) N,N'-Carbonyldiimidazole,97% N,N'-CARBONYL-BIS-(IMIDAZOLE) N,NCARBONYLDIIMIDAZOLE,HIGHPURITY N,N'-Carbonyldiimidazole 98% 1,1''-CARBONYLDIIMIDZOLE CDI 1,1''-CARBONYLDIIMIDAZOLE N.N''-CARBONYL DICMIDAZOLE 1H-Imidazole,1,1-carbonylbis-(9CI) Bis(iMidazol-1-yl) Ketone Bis(iMidazol-1-yl)Methanone NSC 67203 1,1-CarbonyldiMidazole 1,1'-Carbonylbis-1H-imidazole CDI 1,1'-CarbonyldiiMdazole 1,1''-CARBONYLDIIMIDAZOLE FOR SYNTHESIS CarbonyldiiMaidiazole